From c038740be3e0dec1798c0c660081f1b6d2445907 Mon Sep 17 00:00:00 2001 From: Calvin Morrison Date: Wed, 26 Feb 2014 13:38:43 -0500 Subject: update sparse --- kmer_utils.c | 139 ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++- 1 file changed, 137 insertions(+), 2 deletions(-) (limited to 'kmer_utils.c') diff --git a/kmer_utils.c b/kmer_utils.c index f2057ee..b456f2f 100644 --- a/kmer_utils.c +++ b/kmer_utils.c @@ -157,7 +157,7 @@ size_t strnstrip(char *s, int c, size_t len) { } -node * get_kmer_counts_from_file(FILE *fh, const unsigned int kmer) { +node * get_sparse_kmer_counts_from_file(FILE *fh, const unsigned int kmer) { char *line = NULL; size_t len = 0; @@ -236,6 +236,75 @@ node * get_kmer_counts_from_file(FILE *fh, const unsigned int kmer) { } +unsigned long long * get_dense_kmer_counts_from_file(FILE *fh, const unsigned int kmer) { + + char *line = NULL; + size_t len = 0; + ssize_t read; + + long long i = 0; + long long position = 0; + + // width is 4^kmer + const unsigned long long width = pow_four(kmer); + + unsigned long long *counts = malloc(width+1 * sizeof(unsigned long long)); + while ((read = getdelim(&line, &len, '>', fh)) != -1) { + size_t k; + char *seq; + size_t seq_length; + + // find our first \n, this should be the end of the header + seq = strchr(line, '\n'); + if(seq == NULL) + continue; + + // point to one past that. + seq = seq + 1; + + // strip out all other newlines to handle multiline sequences + strnstrip(seq, '\n', strlen(seq)); + seq_length = strlen(seq); + + // relace A, C, G and T with 0, 1, 2, 3 respectively + // everything else is 5 + for(k = 0; k < seq_length; k++) + seq[k] = alpha[(int)seq[k]]; + + + // loop through our seq to process each k-mer + for(position = 0; position < (signed)(seq_length - kmer + 1); position++) { + unsigned long long mer = 0; + unsigned long long multiply = 1; + + // for each char in the k-mer check if it is an error char + for(i = position + kmer - 1; i >= position; i--){ + if(seq[i] == 5) { + mer = width; + position = i; + goto next; + } + + // multiply this char in the mer by the multiply + // and bitshift the multiply for the next round + mer += seq[i] * multiply; + multiply = multiply << 2; + } + // use this point to get mer of our loop + next: + { + // bump up the mer value in the counts array + counts[mer]++; + } + } + } + + //free(line); + fclose(fh); + return counts; + +} + unsigned long long * get_kmer_counts_from_filename(const char *fn, const unsigned int kmer) { FILE *fh = fopen(fn, "r"); if(fh == NULL) { @@ -243,6 +312,72 @@ unsigned long long * get_kmer_counts_from_filename(const char *fn, const unsigne return 0; } - return get_kmer_counts_from_file(fh, kmer); + return get_dense_kmer_counts_from_file(fh, kmer); } +void print_dense(unsigned long long *counts, bool label, bool nonzero, unsigned int kmer) { + size_t width = pow_four(kmer); + size_t i = 0; + + // If nonzero is set, only print non zeros + if(nonzero) { + // if labels is set, print out our labels + if(label) { + for(i = 0; i < width; i++) + if(counts[i] != 0) { + char *kmer_str = index_to_kmer(i, kmer); + fprintf(stdout, "%s\t%llu\n", kmer_str, counts[i]); + free(kmer_str); + } + + } + else { + for(i = 0; i < width; i++) + if(counts[i] != 0) + fprintf(stdout, "%llu\t%llu\n", i, counts[i]); + + } + } + // If we aren't printing nonzeros print everything + else { + if(label) { + for(i = 0; i < width; i++) { + char *kmer_str = index_to_kmer(i, kmer); + fprintf(stdout, "%s\t%llu\n", kmer_str, counts[i]); + free(kmer_str); + } + } + else { + for(i = 0; i < width; i=i+4) { + fprintf(stdout, "%llu\n%llu\n%llu\n%llu\n", counts[i], counts[i+1], counts[i+2], counts[i+3]); + } + } + + } +} + +void print_sparse(node *tree, bool label, bool nonzero, unsigned int kmer) { + + if (tree) { + print_sparse(tree->left, label, nonzero, kmer); + if(label && nonzero) { + char *kmer_str = index_to_kmer(tree->index, kmer); + if (tree->value != 0) + fprintf(stdout, "%s\t%llu\n", kmer_str, tree->value); + free(kmer_str); + } + else if(label) { + char *kmer_str = index_to_kmer(tree->index, kmer); + fprintf(stdout, "%s\t%llu\n", kmer_str, tree->value); + free(kmer_str); + } + else if(nonzero) { + if (tree->value != 0) + fprintf(stdout, "%zu\t%llu\n", tree->index, tree->value); + } + else + fprintf(stdout, "%llu\n", tree->value); + + print_sparse(tree->right, label, nonzero, kmer); + } +} -- cgit v1.2.3